For all of 2010, Ford reported net income of $6.6 billion, or $1.66 per share, up 135 percent from 2009.
The earnings came in below analysts' forecasts of $2.08 per share.
Advertisement: Story continues below
"This was Ford's highest net income in more than 10 years, as strong products and new investments fueled improvements in all of the company's business operations around the world," the Dearborn, Michigan-based automaker said in a statement.
Ford, the only major US automaker that did not take a government bailout during the financial crisis, reported its seventh consecutive quarterly profit, despite a large charge related to paying down debt.